Anti-aging medicine in San Diego has matured into a physician-driven field that goes far beyond injectables and quick fixes.
Today’s top practices bring cellular-level interventions to patients through hormone optimization, regenerative protocols, IV therapies, and functional diagnostics that target root causes.
The concierge model fits naturally here because genuine anti-aging care demands individualized plans, ongoing lab monitoring, and direct physician access, things that rushed 15-minute appointments simply can’t support.
Selecting a provider without verified medical credentials, subspecialty training, or personalized protocols can mean wasted time and money at best, or real harm at worst.
This guide walks through five concierge physicians and practices in San Diego that offer medically sound, advanced anti-aging treatments across longevity clinics, aesthetic specialists, and integrative health centers.
How to Select Top Anti-Aging Concierge Physicians
This research drew from official practice websites, physician credential databases, medical board records, and published professional affiliations in early 2026. Every provider below was evaluated using the same five standards.
Selection Criteria:
Board certification and credentials: All featured physicians hold active board certifications and verifiable medical degrees from accredited institutions, not just aesthetic or wellness certifications.
Subspecialty anti-aging training: Preference went to physicians with formal fellowship training, recognized certifications, or decades of focused clinical experience in anti-aging, longevity, or regenerative medicine.
Breadth of treatment protocols: Practices offering multiple intervention types (hormonal, regenerative, IV-based, aesthetic, and functional diagnostic) were prioritized over single-service providers.
Personalized treatment planning: Each practice must design individualized protocols based on lab results, patient history, and health goals rather than applying one-size-fits-all programs.
Physician-led care delivery: Only practices where a board-certified physician directly oversees and administers treatments were included, not those delegating entirely to nurses or aestheticians.
List of the Best Anti-Aging Concierge Physicians in San Diego
Here are five concierge physicians in San Diego who meet these standards.
- Unify Care
- San Diego Concierge Medicine (Dr. Donna Ni)
- Fontaine MD (Dr. James Fontaine)
- AgeReversalMD (Dr. Phillip Milgram)
- Peak Health Group
Best Anti-Aging Concierge Physicians in San Diego
1. Unify Care
Physicians: Board-certified physicians Dr. Haik Yanashyan and Dr. Kate Mower; specialties include primary care, pulmonary medicine, critical care, and longevity medicine
Anti-aging services: Hormone replacement therapy (including testosterone), peptide therapy, IV infusion, advanced biomarker screening (100+ health markers), nutritional counseling, metabolic health assessments, and anti-aging injectables
Delivery model: In-home concierge visits across 20+ San Diego zip codes; also covers Orange County, Los Angeles, Riverside, and Palm Springs; HIPAA-compliant, evidence-based protocols
Membership plans: Standard ($499/month): 5 house calls + unlimited telehealth; Premium ($999/month): 10 house calls + 24/7 telehealth + comprehensive diagnostics and hospital visit coordination
Standards: 100% evidence-based medicine; board-certified physician oversight; 30-minute response commitment for in-home scheduling; Pay-Per-Visit option available for non-members
Company Overview
Unify Care sends board-certified physicians straight to your door across San Diego and surrounding Southern California regions, combining primary care with longevity and anti-aging subspecialties. If you prefer concierge medical care in San Diego that meets you where you are, this practice delivers hormone replacement therapy (including testosterone), peptide protocols, IV infusions, metabolic health assessments, and biomarker screening that examines more than 100 markers, all inside your home and grounded in evidence-based protocols. Two membership tiers serve different needs: Standard ($499/month) and Premium ($999/month), with a Pay-Per-Visit option for patients who want flexibility without a long-term commitment.
Best For: Patients seeking in-home physician-led anti-aging and longevity care across San Diego with subspecialty pulmonary and critical care support in the same membership.
Standout Feature: Advanced biomarker screening examining 100+ health markers, delivered at home alongside hormone therapy and peptide protocols under board-certified physician oversight.
2. San Diego Concierge Medicine (Dr. Donna Ni)
Physician: Dr. Donna Ni, DO, board-certified in Family Medicine (American Board of Family Medicine); medical degree from Western University of Health Sciences, College of Osteopathic Medicine of the Pacific; residency in family medicine at UC Irvine; former staff physician at U.S. Navy Medical Center San Diego
Established: 2012; 9750 Miramar Road, Suite 215, San Diego, CA 92126
Anti-aging services: Botox, Juvederm, Kybella, RF microneedling, AviClear laser, Aquagold microneedling, HydraFacial MD, chemical peels, IV infusion therapy, B12 injections, Ozempic/semaglutide, glutathione, IV glamour and IV weight loss; dermaplane facial
Allergan credential: Allergan Brilliant Distinction provider; physicians perform all injections personally
Mobile service: Team available to travel to patient’s home or workplace for treatments; telehealth available; complimentary 10-minute consultation offered
Company Overview
San Diego Concierge Medicine opened its doors in 2012 under the direction of Dr. Donna Ni, DO, a board-certified family medicine physician who completed her residency at UC Irvine and served as a staff physician at the U.S. Navy Medical Center San Diego. This practice focuses on evidence-based anti-aging medicine and non-surgical cosmetic dermatology, spanning laser treatments like AviClear, injectables, RF microneedling, IV infusion, and medical weight management including semaglutide. All Botox and filler injections are performed personally by physicians, not handed off to other staff, and the practice holds Allergan Brilliant Distinction provider status.
Best For: Patients looking for a physician-performed aesthetic and wellness practice with mobile service options and an Allergan-credentialed injector.
Standout Feature: Physician-only injectable administration, all Botox and filler treatments are personally performed by a doctor, not delegated to nurses or aestheticians, at this Allergan Brilliant Distinction practice.
3. Fontaine MD (Dr. James Fontaine)
Physician: Dr. James Fontaine, MD, board-certified in Physical Medicine & Rehabilitation; graduate of USC Keck School of Medicine (Class of 1990); residency at UC Irvine/UC Irvine Medical Center; 35+ years of experience; 4765 Carmel Mountain Rd, Suite 207B, San Diego, CA 92130
Anti-aging fellowship: Aesthetic Fellowship through the American Academy of Anti-Aging Medicine (A4M); BHRT training with Dr. Neal Rouzier, a world authority on natural hormone replacement
Anti-aging services: Bioidentical hormone replacement therapy (BHRT) for men and women; testosterone optimization; adult stem cell therapy; PRP injections; non-invasive body sculpting; skin tightening; Botox, Dysport, Juvéderm, Restylane, Sculptra; laser care (photofacial, skin resurfacing); erectile dysfunction treatments; cardiovascular prevention
Model: Concierge-level, individualized, data-driven care; personalized lab-guided treatment plans
Focus: Longevity, healthy aging, aesthetic expertise, and bio-identical hormone optimization with more than 25 years of specialization
Company Overview
Dr. James Fontaine earned his medical degree from USC’s Keck School of Medicine in 1990 and now brings more than 35 years of clinical experience to a concierge-level anti-aging and longevity practice in San Diego’s Torrey Hills neighborhood. He completed an Aesthetic Fellowship through the American Academy of Anti-Aging Medicine and received direct BHRT training under Dr. Neal Rouzier, a globally recognized authority in natural hormone therapy. His services blend bioidentical hormone optimization, regenerative medicine (stem cell therapy, PRP), full-spectrum aesthetic treatments, and cardiovascular prevention within personalized, lab-guided care plans.
Best For: Patients seeking a formally fellowship-trained anti-aging physician with deep expertise in bioidentical hormone therapy and a full suite of aesthetic and regenerative treatments.
Standout Feature: An Aesthetic Fellowship from the American Academy of Anti-Aging Medicine, combined with direct BHRT training under internationally renowned hormone specialist Dr. Neal Rouzier.
4. AgeReversalMD (Dr. Phillip Milgram)
Physician: Dr. Phillip Milgram, MD, board-certified; re-certifies annually; 47+ years of clinical experience; private practice since 1980; graduated Guadalajara, Auton University (1975); former Clinical Instructor and Assistant Clinical Professor at UCSD School of Medicine; holds three degrees from UCSD in Advanced Intervention; affiliated with Scripps Memorial Hospital La Jolla
Specialties and certifications: Certified Affiliate of Global Apheresis in Therapeutic Plasma Exchange (TPE); certified in VSEL therapy; certified Ketamine Provider (The Ketamine Academy); member of American College of Preventive Medicine and American Nutraceutical Association; founder of Anti-Aging San Diego (1984) and NAD MD Inc. (2014)
Anti-aging services: Therapeutic Plasma Exchange (TPE, FDA-cleared for 80+ conditions); IV NAD+ therapy; VSEL laser-activated stem cell therapy; bioidentical hormone therapy; peptide therapy; PRP therapy; ketamine therapy (IV and IM); drug and alcohol detox; vitamin IV therapy
Lab partnerships: Partners with 33+ specialty laboratories for individualized testing including NAD+ cellular energy levels, pharmacogenetics, hormone panels, and micronutrient assessments
Location: La Jolla, California; over 200 TPE procedures performed; known as “The NAD MD”
Company Overview
AgeReversalMD operates as a physician-led longevity clinic in La Jolla under the direction of Dr. Phillip Milgram, MD, a board-certified physician with over 47 years in private practice, a former UCSD School of Medicine faculty member, and the founder of Anti-Aging San Diego (1984) and NAD MD Inc. (2014).
This clinic specializes in cellular-level interventions including Therapeutic Plasma Exchange (FDA-cleared for 80+ conditions), IV NAD+ therapy, VSEL stem cell activation, bioidentical hormone therapy, and certified ketamine treatment, all guided by individualized lab protocols drawn from partnerships with 33+ specialty laboratories.
Best For: Patients seeking the most advanced cellular and regenerative anti-aging protocols in San Diego, including TPE and NAD+ therapy, under a physician with 47+ years of longevity medicine experience.
Standout Feature: Therapeutic Plasma Exchange (TPE), an FDA-cleared procedure validated for 80+ conditions, combined with VSEL laser-activated stem cell therapy and IV NAD+ protocols, with over 200 TPE procedures completed at this La Jolla clinic.
5. Peak Health Group
Physician: Dr. Patrick Yassini, MD, ABIHM, Diplomate, American Board of Family Medicine; Diplomate, American Board of Integrative and Holistic Medicine; Diplomate, American Academy of Anti-Aging Medicine; BS, MS, MD degrees; trained in family medicine at UCSD; Associate Clinical Professor at UCSD; president and current board member of the San Diego Academy of Family Physicians
Established: 2000; 120 C Ave, Suite 140, Coronado, CA 92118
Anti-aging services: Bioidentical hormone replacement therapy (men and women), testosterone therapy, Botox, dermal fillers, PRP facial, PRP facelift, PRP injections, P-Shots, O-Shots, thread lifts, RF microneedling, IV nutrition therapy, B12 and glutathione shots, medical weight loss, acupuncture, acne laser treatments, transgender hormone therapy
Membership: Total Priority Care annual membership; featured in the San Diego Reader and Fox News; 24/7 access to personal physician included
Model: Integrative holistic approach blending Western medicine, acupuncture, botanical medicine, IV nutrition, and aesthetic procedures under one coordinated medical team at the Center for Integrative Medicine in Coronado
Company Overview
Peak Health Group opened in 2000 in Coronado under the leadership of Dr. Patrick Yassini, MD, ABIHM, a UCSD-trained physician who holds triple board credentials in Family Medicine, Integrative and Holistic Medicine, and Anti-Aging Medicine. This practice functions as a full-spectrum integrative anti-aging center, blending bioidentical hormone therapy, PRP regenerative treatments, aesthetic procedures, IV nutrition, and acupuncture under one roof. The Total Priority Care annual membership grants 24/7 physician access and has received coverage from the San Diego Reader and Fox News.
Best For: Patients in Coronado and greater San Diego who want a triple board-certified anti-aging physician with an integrated holistic clinic that covers aesthetics, hormones, regenerative medicine, and primary care in one location.
Standout Feature: Triple board certification in Family Medicine, Integrative and Holistic Medicine, and Anti-Aging Medicine, one of the broadest credential combinations among San Diego anti-aging concierge providers, under one annual membership with 24/7 physician access.
Factors to Consider When Choosing an Anti-Aging Concierge Physician
Verify Medical Credentials Before Treatment
Confirm that the physician is an actively board-certified MD or DO, not just a wellness practitioner or certified nurse injector, and that their certification covers a specialty relevant to anti-aging, internal medicine, or regenerative medicine.
Match the Treatment Type to Your Goals
Hormone optimization, regenerative medicine (TPE, PRP, stem cells), and aesthetic treatments are distinct disciplines. Identify your primary goals first and look for a physician whose training and services align directly with them.
Understand What “Personalized” Actually Means
True personalization requires comprehensive lab testing before treatment begins, not a generic starting protocol. Ask each practice how they establish your baseline and how frequently they adjust your plan based on results.
Confirm Physician vs. Delegated Care
In some practices, the physician creates the plan but treatments are administered by nurses or aestheticians. If physician-delivered care matters to you, confirm this explicitly before enrolling.
Evaluate the Full Membership Cost Realistically
Anti-aging concierge memberships in San Diego range widely in price and scope. Calculate the all-in annual cost including lab testing, infusions, and treatments, not just the base membership fee, to make a meaningful comparison.
Consider Complementary Herbal and Nutritional Support
Many patients pursuing longevity protocols find value in pairing physician-led treatments with plant-based nutritional support. Resources like Alkaline Herb Shop offer herbal supplements designed to support cellular health and overall wellness, which can complement the dietary and metabolic goals your concierge physician sets for you.
Final Thoughts
The most effective anti-aging treatments start with a thorough medical evaluation before any hormone, IV, or aesthetic protocol begins, and they require ongoing lab monitoring and plan adjustment over time. Physician credentials matter.
A fellowship in anti-aging medicine, board certification in a relevant specialty, and years of focused clinical experience are all meaningful differentiators when selecting a provider.
Schedule a consultation with at least two practices before committing. Ask each physician directly about their diagnostic process, how they individualize protocols, and what outcomes you can realistically expect. Real results come from physicians who listen, test thoroughly, and adjust care as your body changes.
